Synthesis and characterization of pHLIP ® coated gold nanoparticles

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Synthesis and characterization of pHLIP® coated gold nanoparticles

Novel approaches in synthesis of spherical and multispiked gold nanoparticles coated with polyethylene glycol (PEG) and pH Low Insertion Peptide (pHLIP®) were introduced. The presence of a tumor-targeting pHLIP® peptide in the nanoparticle coating enhances the stability of particles in solution and promotes a pH-dependent cellular uptake. The spherical particles were prepared with sodium citrat...

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ژورنال

عنوان ژورنال: Biochemistry and Biophysics Reports

سال: 2017

ISSN: 2405-5808

DOI: 10.1016/j.bbrep.2017.02.008